Introduction
L. plantarum is an appreciated functional microorganism due to both its recognized potential health benefits (including survivability in GI tract, adhesion ability, antioxidant capacity, antimicrobial activity, and modulation of the intestinal microbiota) and its ability to improve nutritional and sensory quality of certain foods, and its capacity to extend the shelf-life of fermented foods. These characteristics have made L. plantarum widely utilised as a probiotic culture in a broad variety of foodstuffs, some of its strains being promising cultures in the food industry in terms of enhancing novel and functional products.
Nonetheless, despite the recognized functional properties of different
L. plantarum strains, there are currently many tasks to understand the role that this microorganism plays in the in the host health. Thus, further investigations are needed to characterize the molecular mechanisms by which
L. plantarum exerts its probiotic effects. In this field, omics approaches are gaining importance because they enhance the understanding of the mechanisms behind the functional and probiotic properties of certain beneficial strains such as
L. plantarum. Specifically, the use of metagenomics, transcriptomics, and proteomics allow the study of biological metabolites, the knowledge of gene expression, and the analysis of the complete set of proteins, respectively. These techniques have supported to better understand the mechanisms responsible for some functional properties of L. plantarum such as the mechanisms of adhesion to gastrointestinal tract, its ability to form biofilms, its antimicrobial and antifungal power, and its resistance to certain harsh conditions.
Effects caused in the gut microbiota after the administration of certain probiotics.
Analyses of microbiome composition in pre- and post-treatment fecal samples by 16S rRNA sequencing: (A) The principal component analysis (PCA) revealed no difference in composition between the pre- and post-treatment fecal samples at the phylum level (P=0.479, ANOSIM). (B) The PCA analysis revealed no difference in composition between the pre- and post-treatment fecal samples at the genus level (P=0.841, ANOSIM). (C) The relative abundance of microbial phyla between the pre- and post-treatment samples was indistinguishable (P=0.479, ANOSIM analysis). (D) The relative abundance of microbial genera between the pre- and post-treatment samples was indistinguishable (P=0.841, ANOSIM).
Analyses of microbiome composition differences in major genera and species between the pre- and post-treatment fecal samples by the Wilcoxon rank-sum test: (A) bar plots demonstrating no significant changes in major genera abundance between the pre- and post-treatment (red and blue, respectively) fecal samples (all P>0.05, Wilcoxon rank-sum test); (B) bar plots demonstrating no significant difference in abundance of major species between the pre- and post-treatment fecal samples (all P>0.05, Wilcoxon rank-sum test).
Clusters of Orthologous Group (COG) and Gene Ontology (GO) classifications of functional proteins in the genome of L. plantarum L p3a: (A) protein-coding genes were clustered into 20 COG functional categories, including general function prediction only (484 unigenes), function unknown (352 unigenes), carbohydrate transport and metabolism (235 unigenes), amino acid transport (199 unigenes), and metabolism and transcription (198 unigenes); (B) protein-coding genes were clustered into 31 major GO subclasses, including molecular function (10 unigenes), biological process (11 unigenes), and cellular component (10 unigenes).
Dosage
Follow your phycisian's guidance or instructions enclosed.
Storage
Keep at 5-15 DC and dry out of sunlight, keep away from children.
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Related: Lactobacillus plantarum LP-KFY04/ Lactobacillus plantarum JLA-9/ Lactobacillus plantarum TH103