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L. fermentum has an anti-inflammatory effect in diverse inflammatory diseases.
L. fermentum can modulate both innate and adaptive immune processes.
L. fermentum commonly lessened TNF-α and increased IL-10 in inflammatory tissues.
Immunomodulatory properties of L. fermentum are strain-dependent.
L. fermentum participates in immune regulation.
Many L. fermentum have demonstrated capacity to promote a Th1 response and participated in the regulation of a series of inflammatory cytokines in inflammatory diseases. Immunomodulatory properties are strain-dependent, and further evidence is needed in order to give to each L. fermentum a specific immune response in the intestinal mucosa.